How Transamin has the hemostatic effect?

Tranexamic acid firmly binds to the lysine binding site (LBS), which is the fibrin affinity site of plasmin or plasminogen, and prevents access of plasmin or plasminogen to the fibrin molecule. Therefore, degradation of fibrin by plasmin is strongly inhibited. Tranexamic acid is considered to stop bleeding by blocking the degradation of fibrin.

Advertisements

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out /  Change )

Google+ photo

You are commenting using your Google+ account. Log Out /  Change )

Twitter picture

You are commenting using your Twitter account. Log Out /  Change )

Facebook photo

You are commenting using your Facebook account. Log Out /  Change )

Connecting to %s


%d bloggers like this: